The comparison of analgesic effects of local anesthesia and piroxicam in legal abortions

The comparison of analgesic effects of local anesthesia and piroxicam in

legal abortions

E.Z. Tuzcular Vural, I. Gönenç, N. Aka, G. Köse, K. Karaca

Department of Obstetrics and Gynecology, Haydarpasa Numune Training and

Research Hospital, Istanbul, Turkey

Aim: In this prospective study our aim was to determine whether

piroxicam (P) used either alone or combined with the local anesthetic Lidocaine

hydrochloride (LH) had any superiority over local anesthesia alone or placebo,

and decide whether piroxicam could be used as a safe, economical and efficacious

alternative for pain control.

Materials and Methods: 177 women requesting termination of pregnancy

were included in our study. The participants were double blindly and randomly

divided into four groups. Group 1 (n=40) only used placebo orally, Group 2

(n=48) had only paracervical blocking with LH, Group 3 (n=48) received only 40

mg P administered sublingually, and Group 4 (n=41) had both LH and P. All of the

pregnancies were terminated by means of suction curettage using nr: 5 and 6

flexible Karman canulas and a Karman injector. 10 minutes after the procedure,

all of the participants were questioned for pain perception using the five-point

pain scale. x2, Mann-Whitney U, Levene, Anova tests and

Kruskal-Wallis one way variable analysis and Pearson correlation tests were used

for statistical evaluation of the data.

Results: Pain scores were the highest in Group 1 (p<0,05). Group 2, Group 3 and Group 4 followed respectively. P combined with LH both clinically and statistically gave the best results for pain control (p<0,05).

Conclusion: We conclude that premedication with P and paracervical

blocking with LH is a safe, economical and easy to apply way of pain management

in legal abortion procedures.

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