The breast tenderness during using transdermal contraception with evening
primrose oil and vitamin E
A. Korenek, J. Skalicka, A.Ilik, M. Sabata
Department of Obstetrics and Gynecology, Jesenická nemocnice Hospital,
Jeseník, Czech Republic
Objective: The aim of study was to investigate the effect of the
evening primrose oil with vitamin E on the breast tenderness during the first
three months of using transdermal contraception EVRA ® (Jansen Cilag).
Patients and methods: A total 38 patients, aged between 19 and 25
years, received a transdermal contraception (EVRA®, Jansen Cilag) containing
norelgestromium 150 µg and ethinyl estradiol 20µg per day. All patients was
split in two groups: group A: 19 patients were using EVRA patchs with one pill
per day containing 500 mg evening oil primrose and 40mg vitamin E. Group B: 19
patients were using just EVRA patchs. We compare breast tenderness between that
two groups for three month.
Results: Data were evaluated from all 38 patients (114 cycles), from
group A firsth month had breast tenderness 3 (15,7%) and third month nobody, in
group B firsth month had tenderness 10 (52,6%) and third month 1 (5,2%).
Conclusion: Using evening primrose oil with vitamin E can decrease
breast tenderness during using in firsth months of receiving contraceptive
patchs, usually tenderness disappeared at the latest after third months.
