The effect of the use of the combine oral contraceptive,
intrauterine contraceptive device and subdermal contraceptive implant on basal
ovarian volume
L Karci, B Cetinkaya, A Baloglu, I Bezircioglu
Aegean University,
Obstetric and Gynecology Department, Izmir, Turkey
Objective The aim of this
study was to investigate the effect of the use of the oral contraceptive, the
intrauterine contraceptive device and subdermal contraceptive implant on basal
ovarian volume.
Material and methods We included 60 healthy women who applied
to Department of Family Planning Izmir Ataturk Educational Hospital. We
investigated the cases as 3 groups. In the first group there were 20 cases who
were using oral contraceptive, in the second group 20 cases who were using
intrauterine contraceptive device and in the third group 20 cases who were using
subdermal contraceptive implant. The volume of the ovaries was measured before
treatment and six months after the beginning of the treatment by transvaginal
ultrasonography. The study groups were investigated for parity, body mass index
(BMI kg/m2), and menarche age in terms of the effect to ovarian volume.
Results
Ovarian volume was significantly smaller in subdermal contraceptive implant and
oral contraceptive groups. (p:0,0001, p:0,0001). There was no statistical
difference in ovarian volume in the intrauterine contraceptive device group
(p:0,823) .No association was observed between beginning ovarian volume and BMI
and menarche (p:0,53; p:0,863) but age and parity showed a significant positive
correlation with ovarian volume (p:0,0004; p:0,012).
Conclusion This study
showed us that ovarian volume decreases in oral contraceptive users and
subdermal contraceptive implant users. There were no correlation between the
intrauterine contraceptive device and ovarian volume. Ovarian volume decreased
with aging and parity but no association was observed between ovarian volume and
body mass index and menarche.